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    <IdentifierDoi>10.3205/26kgg247</IdentifierDoi>
    <IdentifierUrn>urn:nbn:de:0183-26kgg2473</IdentifierUrn>
    <ArticleType>Meeting Abstract</ArticleType>
    <TitleGroup>
      <Title language="en">Harvest plots in evidence syntheses: a meta-research study on their use and characteristics</Title>
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        <PersonNames>
          <Lastname>Hirt</Lastname>
          <LastnameHeading>Hirt</LastnameHeading>
          <Firstname>Julian</Firstname>
          <Initials>J</Initials>
        </PersonNames>
        <Address>
          <Affiliation>Eastern Switzerland University of Applied Sciences, Department of Health, Schweiz</Affiliation>
          <Affiliation>Martin Luther University Halle-Wittenberg, Medical Faculty, Institute of Health, Midwifery and Nursing Science, Deutschland</Affiliation>
          <Affiliation>University of Bern, Faculty of Medicine, Department of Clinical Research, Bern, Schweiz</Affiliation>
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      <Creator>
        <PersonNames>
          <Lastname>Mersdorf</Lastname>
          <LastnameHeading>Mersdorf</LastnameHeading>
          <Firstname>Benedikt</Firstname>
          <Initials>B</Initials>
        </PersonNames>
        <Address>
          <Affiliation>Martin Luther University Halle-Wittenberg, Medical Faculty, Institute of Health, Midwifery and Nursing Science, Deutschland</Affiliation>
          <Affiliation>University Hospital Augsburg, Emergency Department, Augsburg, Deutschland</Affiliation>
        </Address>
        <Creatorrole corresponding="no" presenting="no">author</Creatorrole>
      </Creator>
      <Creator>
        <PersonNames>
          <Lastname>Pellegrino</Lastname>
          <LastnameHeading>Pellegrino</LastnameHeading>
          <Firstname>Melanie</Firstname>
          <Initials>M</Initials>
        </PersonNames>
        <Address>
          <Affiliation>ETH Z&#252;rich, Department of Health Sciences and Technology, Schweiz</Affiliation>
        </Address>
        <Creatorrole corresponding="no" presenting="no">author</Creatorrole>
      </Creator>
      <Creator>
        <PersonNames>
          <Lastname>Meyer</Lastname>
          <LastnameHeading>Meyer</LastnameHeading>
          <Firstname>Gabriele</Firstname>
          <Initials>G</Initials>
        </PersonNames>
        <Address>
          <Affiliation>Martin Luther University Halle-Wittenberg, Medical Faculty, Institute of Health, Midwifery and Nursing Science, Deutschland</Affiliation>
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        <Creatorrole corresponding="no" presenting="no">author</Creatorrole>
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          <Corporatename>German Medical Science GMS Publishing House</Corporatename>
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        <Address>D&#252;sseldorf</Address>
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      <SubjectheadingDDB>610</SubjectheadingDDB>
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    <DatePublishedList>
      <DatePublished>20251030</DatePublished>
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    <Language>engl</Language>
    <License license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
      <AltText language="en">This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License.</AltText>
      <AltText language="de">Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung).</AltText>
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      <Meeting>
        <MeetingId>M0662</MeetingId>
        <MeetingSequence>247</MeetingSequence>
        <MeetingCorporation>Deutsche Gesellschaft f&#252;r Allgemeinmedizin und Familienmedizin</MeetingCorporation>
        <MeetingCorporation>Deutsche Gesellschaft f&#252;r Sozialmedizin und Pr&#228;vention</MeetingCorporation>
        <MeetingCorporation>Netzwerk Evidenzbasierte Medizin e.V.</MeetingCorporation>
        <MeetingCorporation>Deutsche Gesellschaft f&#252;r Medizinische Soziologie</MeetingCorporation>
        <MeetingName>60. Kongress f&#252;r Allgemeinmedizin und Familienmedizin</MeetingName>
        <MeetingTitle>Gesundheit gestalten</MeetingTitle>
        <MeetingSession>Methoden der Gesundheitsforschung II</MeetingSession>
        <MeetingCity>G&#246;ttingen</MeetingCity>
        <MeetingDate>
          <DateFrom>20260930</DateFrom>
          <DateTo>20261002</DateTo>
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    <ArticleNo>V-45-02</ArticleNo>
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      <MainHeadline>Text</MainHeadline><Pgraph><Mark1>Background:</Mark1> Harvest plots are a graphical method for the presentation of complex and heterogeneous evidence in health-related evidence syntheses. Their design and use are not standardized.</Pgraph><Pgraph><Mark1>Aim&#47;scientific question:</Mark1> To provide a systematic overview of the use and methodological characteristics of harvest plots in the context of health-related evidence syntheses.</Pgraph><Pgraph><Mark1>Material &#38; Methods:</Mark1> We used a meta-research approach to capture existing research and publication practices. The study protocol was prospectively registered on Open Science Framework (10.17605&#47;OSF.IO&#47;75V6X). We included evidence syntheses on a health-related research question that used and reported a harvest plot for data analysis and synthesis. The search was carried out in PubMed and Embase. We performed a forward citation search of the original 2008 publication, in which the harvest plot was incepted. The selection and extraction of data was mainly carried out by one reviewer and double-checked by a second reviewer, with no formal quality assurance of the included studies.</Pgraph><Pgraph><Mark1>Results:</Mark1> We included 201 harvest plots to our analysis, published between 2008 and 2025. Study characteristics show that narrative harvest plot descriptions were mainly provided as part of the figure (n&#61;191; 95&#37;). The design of the studies that used a harvest plot was mainly a systematic review (n&#61;186; 93&#37;) including interventional (n&#61;122; 61&#37;) and observational (n&#61;103; 51&#37;) studies. The included harvest plots mainly provide information about intervention or exposure in the row (n&#61;80; 40&#37;), effect direction in the column (n&#61;170; 85&#37;). Bar color indicates mainly study quality (n&#61;27; 13&#37;) or outcome measurement (n&#61;25; 12&#37;). General top or bottom information mainly indicated a study reference (n&#61;114; 57&#37;).</Pgraph><Pgraph><Mark1>Discussion:</Mark1> Our results revealed large heterogeneity and a lack of standardization of the design, illustration, and characteristics when providing a harvest plot in health-related evidence synthesis. Methods guidance in combination with a digitalized tool or program code and reporting guidance may contribute to a higher degree of standardization and facilitate interpretation of harvest plots.</Pgraph><Pgraph><Mark1>Take Home Message:</Mark1> Although harvest plots are being increasingly used, their design varies widely. They are usually limited to just a few dimensions, such as the effect direction, intervention characteristics, and&#47;or the study quality, even though the method offers more possibilities. There is an urgent need to harmonize and standardize through methodological guidance and reporting standard, preferably supported by digital tools.</Pgraph><Pgraph><Mark1>Competing interests:</Mark1> JH and GM authored publications eligible to this meta-research study. All authors declare no conflict of interest.</Pgraph></TextBlock>
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