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    <IdentifierUrn>urn:nbn:de:0183-26doc0643</IdentifierUrn>
    <ArticleType>Meeting Abstract</ArticleType>
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      <Title language="en">Predictors of refractive astigmatism following combined phacoemulsification and vitrectomy in 1,041 eyes with coexisting cataracts and vitreoretinal pathology: A multicenter retrospective cohort study</Title>
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          <Corporatename>German Medical Science GMS Publishing House</Corporatename>
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        <Address>D&#252;sseldorf</Address>
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      <SubjectheadingDDB>610</SubjectheadingDDB>
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    <DatePublishedList>
      <DatePublished>20260617</DatePublished>
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    <Language>engl</Language>
    <License license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
      <AltText language="en">This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License.</AltText>
      <AltText language="de">Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung).</AltText>
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      <Meeting>
        <MeetingId>M0651</MeetingId>
        <MeetingSequence>064</MeetingSequence>
        <MeetingName></MeetingName>
        <MeetingTitle>38. Internationaler Kongress der Deutschen Ophthalmochirurgie (DOC)</MeetingTitle>
        <MeetingSession>Katarakt II</MeetingSession>
        <MeetingCity>N&#252;rnberg</MeetingCity>
        <MeetingDate>
          <DateFrom>20260618</DateFrom>
          <DateTo>20260620</DateTo>
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      <MainHeadline>Text</MainHeadline><Pgraph><Mark1>Purpose:</Mark1> To investigate vectorial astigmatism time course and identify its predictors following combined phacoemulsification and pars plana vitrectomy. </Pgraph><Pgraph><Mark1>Methods:</Mark1> This multicenter retrospective cohort study included 1,041 eyes from 1,041 patients undergoing phacovitrectomy at four centers. Eyes with macula-off retinal detachment, prior vitreoretinal surgery, silicone oil endotamponade, or postoperative CDVA worse than 0.4 (decimal) were excluded. One eye per patient was analyzed. Preoperative astigmatism was derived from keratometry and corrected using the Abulafia&#8211;Koch method, while postoperative astigmatism was obtained from refraction. Astigmatism was vectorially decomposed into J0 and J45 components. Changes over time were assessed using multivariate repeated-measures ANOVA, and predictors of &#916;J0 and &#916;J45 were identified using multivariate linear regression. </Pgraph><Pgraph><Mark1>Results:</Mark1> The orthogonal astigmatism component (J0) decreased from &#43;0.62 &#177; 0.38 D (95&#37; CI: 0.60 to 0.64) preoperatively to &#43;0.05 &#177; 0.45 D (95&#37; CI: 0.02 to 0.08) postoperatively, while the oblique component (J45) increased from 0.003 &#177; 0.25 D (95&#37; CI: -0.01 to 0.02) to &#43;0.04 &#177; 0.30 D (95&#37; CI: 0.02 to 0.05), indicating a systematic vectorial shift (p &#60;0.001, &#951;p&#178; &#61; 0.349). The final regression models demonstrated high predictive accuracy, explaining 88.5&#37; of the variance in &#916;J0 (adjusted R&#178; &#61; 0.885, SEE &#61; 0.267, p &#60;0.001) and 83.5&#37; of the variance in &#916;J45 (adjusted R&#178; &#61; 0.835, SEE &#61; 0.205, p &#60;0.001). Baseline astigmatism was the dominant predictor in both models. Axial length, incision site, and incision meridian significantly predicted &#916;J0, while laterality, incision size, and incision meridian significantly predicted &#916;J45 (all p &#60;0.001). Endotamponade type and gauge size showed no relevant effect. </Pgraph><Pgraph><Mark1>Conclusions:</Mark1> Phacovitrectomy induces minimal but statistically significant changes in astigmatism, characterized by a reduction in with-the-rule component and a small induction of oblique astigma-tism. These changes are highly systematic and predominantly determined by incision characteristics and baseline astigmatism rather than intraocular factors. </Pgraph></TextBlock>
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