26vzmnrw089
10.3205/26vzmnrw089
urn:nbn:de:0183-26vzmnrw0893
Meeting Abstract
Body composition in patients undergoing liver transplantation for hepatocellular carcinoma
Pantea
Pantea
R.
R
Universitätsklinikum Essen, Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Essen, Deutschland
author
Schmitz
Schmitz
S. M.
SM
Universitätsklinikum Essen, Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Essen, Deutschland
author
Hosch
Hosch
R.
R
Universitätsklinikum Essen, Institut für Künstliche Intelligenz in der Medizin; Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Essen, Deutschland
author
Heise
Heise
D.
D
Universitätsklinikum Essen, Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Essen, Deutschland
author
Nensa
Nensa
F.
F
Universitätsklinikum Essen, Institut für Künstliche Intelligenz in der Medizin; Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Essen, Deutschland
author
Neumann
Neumann
U. P.
UP
Universitätsklinikum Essen, Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Essen, Deutschland
author
Oezcelik
Oezcelik
A.
A
Universitätsklinikum Essen, Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Essen, Deutschland
author
German Medical Science GMS Publishing House
Düsseldorf
610
20260618
engl
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung).
M0644
089
Niederrheinisch-Westfälische Gesellschaft für Chirurgie
Gesellschaft für Gastroenterologie in Nordrhein-Westfalen e.V.
192. Jahrestagung der Niederrheinisch-Westfälischen Gesellschaft für Chirurgie, 34. Jahrestagung der Gesellschaft für Gastroenterologie
Viszeralmedizin NRW 2026
Chirurgie
Dortmund
20260618
20260619
089
TextBackground and objective: The prognostic value of body composition on the outcome of various cancer types is well described. However, its impact on recurrence and survival in patients with hepatocellular carcinoma (HCC) undergoing liver transplantation is still unclear. Therefore, this study aimed to evaluate the prognostic relevance of AI-based body composition analysis in HCC patients undergoing liver transplantation.Method: AI-based body composition was assessed in all patients who underwent liver transplantation between 2007 and 2025 due to HCC and had a computed tomography scan of the abdomen available within three months prior to transplantation. Pre-, intra- and postoperative data were retrospectively collected. Patients were stratified according to the lowest 30th percentile of the Sarcopenia Index (SI; most sarcopenic) and the highest 30th percentile of the Myosteatosis Fat Index (MFI) and Visceral Fat Index (VFI) (highest myosteatosis and visceral fat distribution).Result: A total of 126 patients were included. Sarcopenia and myosteatosis were identified as significant independent prognostic parameters for overall survival after transplantation (p=0.048 and p=0.002, respectively), while BMI class and VFI showed no significant influence on survival (p=0.826 and p=0.599).Summary: The results of our study show that sarcopenia and myosteatosis have a significant impact on the outcome of patients with HCC undergoing liver transplantation, while plain abdominal fat does not appear to affect overall survival. Optimal patient selection can be improved by fully automated, AI-based assessment of these factors prior to transplantation.
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