26dga229 10.3205/26dga229 urn:nbn:de:0183-26dga2290 Meeting Abstract Sofack Sofack Ghislain G

Medical Center, Faculty of Medicine, University of Freiburg, Department of Otorhinolaryngology – Head and Neck Surgery, Freiburg i. Br., Deutschland Medical Center, Faculty of Medicine, University of Freiburg, Department of Nuclear Medicine, Freiburg i. Br., Deutschland

author Giegerich Giegerich Ondine O

Medical Center, Faculty of Medicine, University of Freiburg, Department of Otorhinolaryngology – Head and Neck Surgery, Freiburg i. Br., Deutschland

author Aschendorff Aschendorff Antje A

Medical Center, Faculty of Medicine, University of Freiburg, Department of Otorhinolaryngology – Head and Neck Surgery, Freiburg i. Br., Deutschland

author Arndt Arndt Susan S

Medical Center, Faculty of Medicine, University of Freiburg, Department of Otorhinolaryngology – Head and Neck Surgery, Freiburg i. Br., Deutschland

author Glauche Glauche Volkmar V

Medical Center, Faculty of Medicine, University of Freiburg, Department of Neurology and Clinical Neuroscience, Freiburg i. Br., Deutschland

author Musso Musso Mariachristina M

Medical Center, Faculty of Medicine, University of Freiburg, Department of Neurology and Clinical Neuroscience, Freiburg i. Br., Deutschland

author Bormann Bormann Tobias T

Medical Center, Faculty of Medicine, University of Freiburg, Department of Neurology and Clinical Neuroscience, Freiburg i. Br., Deutschland

author Mast Mast Hansjörg H

Medical Center, Faculty of Medicine, University of Freiburg, Department of Neuroradiology, Freiburg i. Br., Deutschland

author Rau Rau Alexander A

Medical Center, Faculty of Medicine, University of Freiburg, Department of Neuroradiology, Freiburg i. Br., Deutschland

author Urbach Urbach Horst H

Medical Center, Faculty of Medicine, University of Freiburg, Department of Neuroradiology, Freiburg i. Br., Deutschland

author Speck Speck Iva I

Medical Center, Faculty of Medicine, University of Freiburg, Department of Nuclear Medicine, Freiburg i. Br., Deutschland

author German Medical Science GMS Publishing House

Düsseldorf

610 20260302 engl This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). M0642 229 Deutsche Gesellschaft für Audiologie e. V. 28. Jahrestagung der Deutschen Gesellschaft für Audiologie Postersession Oldenburg 20260304 20260306 229 TextQuestion: Audiotactile cues can enhance speech perception in noise, yet the neural mechanisms underlying vibrotactile speech processing remain poorly understood, particularly in individuals with single-sided deafness (SSD). The present study investigated how adults with acquired SSD process vibrotactile speech-like stimuli compared to simple vibrotactile frequencies, and how these responses differ from normal-hearing (NH) controls.Methods: Twenty adults with acquired SSD and 20 age- and sex-matched NH controls underwent functional magnetic resonance imaging (fMRI) during vibrotactile stimulation using simple frequencies (125 Hz) and vibrotactile speech-like (VS) paradigms applied to the right index finger. Behavioral performance (hit rates, reaction time) was measured. Region-of-interest analyses quantified activation in primary auditory cortex (PAC) and primary somatosensory cortex (S1). Additional analyses assessed differences in left vs. right SSD and correlations between neural measures and clinical variables.Results: Both groups responded faster to 125 Hz than VS stimuli (p = 0.03). Participants with SSD showed widespread recruitment during vibrotactile speech stimulation, including middle temporal gyrus, superior frontal gyrus and frontal operculum. Regional analyses revealed reduced stimulus selectivity in S1 in SSD compared to NH. Furthermore, robust left-hemisphere dominance was found in PAC for both left and right SSD during both stimuli conditions. Strong associations were present between left superior frontal gyrus activation and clinical factors, including age (r = 0.54, p = 0.01), sound localization (r = –0.57, p = 0.03), and measures of executive memory (r = –0.45, p = 0.04).Conclusion: Vibrotactile speech-like stimuli strongly engage reorganized auditory networks, highlighting their potential relevance for understanding sensory compensation and informing cochlear-implant prognostics. 0 0 0 0