26dga053
10.3205/26dga053
urn:nbn:de:0183-26dga0535
Meeting Abstract
Use of OPM-MEG for identification of the neural correlate of tinnitus
Knipper
Knipper
Marlies
M
Universitäts-HNO-Klinik Tübingen, Hörforschungszentrum, Tübingen, Deutschland
author
Donoso-San Martin
Donoso-San Martin
Rodrigo Andres
RA
Universitäts-HNO-Klinik Tübingen, Hörforschungszentrum, Tübingen, Deutschland
Universidad de Chile, Laboratorio Neurobiologia de la Audicion, Santiago, Chile
author
Wolpert
Wolpert
Stephan
S
Universitäts-HNO-Klinik Tübingen, Hörforschungszentrum, Tübingen, Deutschland
author
Fink
Fink
Stefan
S
Universitäts-HNO-Klinik Tübingen, Hörforschungszentrum, Tübingen, Deutschland
author
Delano
Delano
Paul H.
PH
Universidad de Chile, Laboratorio Neurobiologia de la Audicion, Santiago, Chile
author
Braun
Braun
Christoph
C
Universität Tübingen, MEG-Center, Tübingen, Deutschland
author
Rüttiger
Rüttiger
Lukas
L
Universitäts-HNO-Klinik Tübingen, Hörforschungszentrum, Tübingen, Deutschland
author
German Medical Science GMS Publishing House
Düsseldorf
610
20260302
engl
This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License.
Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung).
M0642
053
Deutsche Gesellschaft für Audiologie e. V.
28. Jahrestagung der Deutschen Gesellschaft für Audiologie
Freie Vorträge 2: Hörgeschädigtenpädagogik & Tinnitus
Oldenburg
20260304
20260306
053
BMBF
TextAcquired auditory processing disorders including age dependent hearing loss, speech discrimination deficits, tinnitus or hyperacusis, require a personalized diagnosis to assign the individual cause within the auditory hierarchy to either the periphery, subcortical, or distinct cortical or cortico-fugal neuronal dysfunctions. The good functioning of the feedforward and feedback PV-IN network is an essential precondition for audition that above all senses relies on high-speed information flow (Zajac IT and Nettelbeck T, 2018). Therefore, we hypothesize disease-specific deficits in temporal intracortical network function in auditory circuits. We studied fast auditory processing in tinnitus subjects with or without the comorbidity of hyperacusis using auditory stimuli evoking time-sensitive cortical responses. These responses were recorded using a time-sensitive OPM-MEG. We expect this method to become an efficient diagnostic strategy to fathom peripheral or central contribution of the distinct auditory impairments in the future to improve individualized targeted interventional therapies. Here we will present preliminary results demonstrating the usability and function of the OPM-MEG for hearing research in a clinical setting.Acknowledgment and funding: This work was supported by ERA-NET NEURON JTC 2020: BMBF 01EW2102 CoSySpeech and the Tübingen Research Take off Program (TRT) of the Brasilien-Lateinamerika Zentrum, University of Tübingen.
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