Risk of falls and fractures in hip and knee osteoarthritis: A multifactorial analysis

25dkou333 10.3205/25dkou333 urn:nbn:de:0183-25dkou3336 Meeting Abstract Risk of falls and fractures in hip and knee osteoarthritis: A multifactorial analysis Sorbi Sorbi Reza R

Klinik für Orthopädie und Unfallchirurgie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, Deutschland Orthopädisches Forschungszentrum, Christian-Albrechts-Universität zu Kiel, Kiel, Deutschland

author Al Tawil Al Tawil Ghaith G

Orthopädisches Forschungszentrum, Christian-Albrechts-Universität zu Kiel, Kiel, Deutschland

author Gantz Gantz Simone S

Orthopädisches Forschungszentrum, Christian-Albrechts-Universität zu Kiel, Kiel, Deutschland

author Pourbozorg Pourbozorg Ghazal G

Orthopädisches Forschungszentrum, Christian-Albrechts-Universität zu Kiel, Kiel, Deutschland

author Mayakrishnan Mayakrishnan Ravikumar R

Orthopädisches Forschungszentrum, Christian-Albrechts-Universität zu Kiel, Kiel, Deutschland

author Moradi Moradi Babak B

author Platzer Platzer Hadrian H

author German Medical Science GMS Publishing House

Düsseldorf

610 20251031 engl This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). M0634 333 Deutsche Gesellschaft für Orthopädie und Unfallchirurgie Deutsche Gesellschaft für Orthopädie und Orthopädische Chirurgie Deutsche Gesellschaft für Unfallchirurgie Berufsverband für Orthopädie und Unfallchirurgie Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2025) Abstracts | Alterstraumatologie allgemein Berlin 20251028 20251031 AB50-4328 TextObjectives and questions: Osteoarthritis (OA) is the most common joint disease, leading to pain, stiffness, and reduced mobility. These impairments may increase the risk of falls and fractures that are exacerbated by comorbidities. Understanding the relationship among OA, falls, fractures, and associated risk factors is crucial for improving risk stratification and targeted prevention. This study investigated whether individuals with hip or knee OA, or both, experience a higher incidence of falls and fractures than those without OA. In addition, this study explored other possible OA-associated risk factors that may contribute to falls and fractures in patients with OA.Material and methods: This study employed a retrospective analysis of the Osteoarthritis Initiative database of the Open Archives Initiative (OAI) in individuals with and without hip and knee OA. Falls and fractures were documented through self-reports within 12 months of OA diagnosis. Potential influencing factors included functional test results, quality of life assessments, depressive symptoms, physical activity levels, and sociodemographic variables. Correlation and logistic regression analyses were conducted to identify predictive factors for falls and fractures, with a focus on hip and/or knee OA.Results: Of the 4,796 OAI participants, 4,427 were included (58.6% female, 41.4% male). Among them, 19.9% (n=880) had knee OA exclusively, 3.6% (n=159) had hip OA exclusively, and 3.7% (n=165) were affected by both conditions. OA (hip, knee, or both) was not significantly associated with an increased risk of falls or fractures. Although quality of life and functional assessments, including the Short Form Health Survey (SF-12) and Knee Injury and Osteoarthritis Outcome Score (KOOS), revealed significant differences between individuals with knee and hip osteoarthritis (OA) and those without OA, these assessments were not found to be significant predictors of fall or fracture risk. However, a higher depression score, female sex (p < 0.01), and advanced age (p < 0.001) were associated with increased fall and fracture risks, respectively.Discussion and conclusions: These findings indicate that hip and/or knee OA does not increase the likelihood of falls or fractures. Instead, mental health, sex, and age-related functional decline play critical roles in individuals with OA. A comprehensive clinical approach to OA management should address both the physical and mental health issues. Prevention strategies to reduce the risk of falls and fractures should focus on alleviating depressive symptoms, improving physical function, and raising physician awareness of these important risk factors to improve the care and education of patients with OA. 0 0 0 0