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    <Identifier>26dkou094</Identifier>
    <IdentifierDoi>10.3205/26dkou094</IdentifierDoi>
    <IdentifierUrn>urn:nbn:de:0183-26dkou0941</IdentifierUrn>
    <ArticleType>Meeting Abstract</ArticleType>
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      <Title language="en">Zone specific suspension and neurovascular histology of the human lateral meniscus: Implications for repair</Title>
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        <PersonNames>
          <Lastname>Selle</Lastname>
          <LastnameHeading>Selle</LastnameHeading>
          <Firstname>Sebastian</Firstname>
          <Initials>S</Initials>
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        <Address>
          <Affiliation>International Center for Orthopedics, ATOS Hospital Heidelberg, Institute for Anatomy and Cell Biology, Ruprecht-Karls University, INF 307, Heidelberg, Deutschland</Affiliation>
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      <Creator>
        <PersonNames>
          <Lastname>Siebold</Lastname>
          <LastnameHeading>Siebold</LastnameHeading>
          <Firstname>Rainer</Firstname>
          <Initials>R</Initials>
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        <Address>
          <Affiliation>International Center for Orthopedics, ATOS Hospital Heidelberg, Institute for Anatomy and Cell Biology, Ruprecht-Karls University, INF 307, Heidelberg, Deutschland</Affiliation>
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        <Creatorrole corresponding="no" presenting="no">author</Creatorrole>
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      <Creator>
        <PersonNames>
          <Lastname>Kirsch</Lastname>
          <LastnameHeading>Kirsch</LastnameHeading>
          <Firstname>Joachim</Firstname>
          <Initials>J</Initials>
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        <Address>
          <Affiliation>International Center for Orthopedics, ATOS Hospital Heidelberg, Institute for Anatomy and Cell Biology, Ruprecht-Karls University, INF 307, Heidelberg, Deutschland</Affiliation>
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        <Creatorrole corresponding="no" presenting="no">author</Creatorrole>
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      <Creator>
        <PersonNames>
          <Lastname>Feil</Lastname>
          <LastnameHeading>Feil</LastnameHeading>
          <Firstname>Sven</Firstname>
          <Initials>S</Initials>
        </PersonNames>
        <Address>
          <Affiliation>International Center for Orthopedics, ATOS Hospital Heidelberg, Heidelberg, Deutschland</Affiliation>
        </Address>
        <Creatorrole corresponding="no" presenting="no">author</Creatorrole>
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          <Corporatename>German Medical Science GMS Publishing House</Corporatename>
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        <Address>D&#252;sseldorf</Address>
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      <SubjectheadingDDB>610</SubjectheadingDDB>
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    <DatePublishedList>
     <DatePublished>20261020</DatePublished>
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    <Language>engl</Language>
    <License license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/4.0/">
      <AltText language="en">This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License.</AltText>
      <AltText language="de">Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung).</AltText>
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      <Meeting>
        <MeetingId>M0659</MeetingId>
        <MeetingSequence>094</MeetingSequence>
        <MeetingCorporation>Deutsche Gesellschaft f&#252;r Orthop&#228;die und Unfallchirurgie</MeetingCorporation>
        <MeetingCorporation>Deutsche Gesellschaft f&#252;r Orthop&#228;die und Orthop&#228;dische Chirurgie</MeetingCorporation>
        <MeetingCorporation>Deutsche Gesellschaft f&#252;r Unfallchirurgie</MeetingCorporation>
        <MeetingCorporation>Berufsverband f&#252;r Orthop&#228;die und Unfallchirurgie</MeetingCorporation>
        <MeetingName></MeetingName>
        <MeetingTitle>Deutscher Kongress f&#252;r Orthop&#228;die und Unfallchirurgie (DKOU 2026)</MeetingTitle>
        <MeetingSession>Abstracts &#124; Knorpeltherapie und Osteochondrale L&#228;sionen</MeetingSession>
        <MeetingCity>Berlin</MeetingCity>
        <MeetingDate>
          <DateFrom>20261020</DateFrom>
          <DateTo>20261023</DateTo>
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    <ArticleNo>DKOU26&#95;Abs&#95;2178</ArticleNo>
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      <MainHeadline>Text</MainHeadline><Pgraph><Mark1>Objectives and questions: </Mark1>To quantify region-dependent variation in meniscosynovial suspension and synovial pouch (SP) architecture of the human lateral meniscus (LM), to map associated neurovascular patterns, and to translate these microanatomical findings into zone-adapted arthroscopic repair concepts (Table 1 <ImgLink imgNo="1" imgType="table" />; Figure 1 <ImgLink imgNo="1" imgType="figure" />).</Pgraph><Pgraph><Mark1>Material and methods: </Mark1>Six fresh-frozen cadaveric knees (mean age 72 years, range 59&#8211;83) were examined in a basic science cadaveric laboratory study. A total of 139 histological section planes were analyzed across five predefined regions (A: anterior horn &#91;AH&#93;; Ba: anterior pars intermedia &#91;aPI&#93;; Bb: posterior pars intermedia &#91;pPI&#93;; C: popliteal hiatus &#91;POH&#93;; D: posterior horn &#91;PH&#93;). Hematoxylin&#8211;eosin&#8211;safran (HES) and Movat&#8217;s pentachrome staining were performed; whole-slide images were digitized; calibrated measurements quantified attachment proportion, vessels and nerve fibers were annotated per region.</Pgraph><Pgraph><Mark1>Results: </Mark1>Meniscal base height attached via meniscosynovial suspension (mean &#177; SD) was A 84 &#177; 3&#37;, Ba 100 &#177; 0&#37;, Bb 62 &#177; 11&#37;, C 47 &#177; 21&#37;, and D 96 &#177; 10&#37;. Region A (loose connective tissue &#91;LCT&#93;, shallow SP, central tract; pacinian corpuscles) supports supra- and&#47;or inframeniscal outside-in repair with minimal intra-articular bulk. Region Ba (two dense connective tissue &#91;DCT&#93; bundles, deep SP, sub&#8211;mid-height neurovascularity in adipose tissue &#91;AT&#93;) favors hybrid fixation (inferior inside-out&#47;outside-in; superior all-inside). Region Bb (inferior DCT insertion well below the tibial plateau &#91;TP&#93;, deep SP, fewer vessels near the base, lateralized larger vessels in AT) suggests primarily inframeniscal base capture with cautious all-inside repair and capsular fixation only when necessary. Region C shows variable, often minimal attachment consistent with popliteomeniscal fascicle (PMF) tissue (inferior iPMF&#47;superior sPMF) and sparse adjacent perimeniscal vascularity; therefore inframeniscal-only, non-bridging, popliteus tendon (PT)- preserving repair anchored to PMF is recommended. Region D (robust converging DCT bundles, small SP, diffuse vessels&#47;nerves at the meniscocapsular transition) permits all-inside or inside-out repair supra- and&#47;or inframeniscally while avoiding overtethering.</Pgraph><Pgraph><Mark1>Discussion and conclusions: </Mark1>Marked regional heterogeneity of LM suspension and neurovascular anatomy supports differentiated selection of suture level, technique, and material rather than uniform repair across the lateral meniscus. Specifically, suspension-dominant and mobile segments (A&#47;Ba&#47;D) warrant constructs that stabilize the base while minimizing long-term capsular tethering, whereas the POH (C) should be treated as a distinct entity with PMF-based, inframeniscal-only fixation to preserve popliteus-dependent kinematics and avoid bridging across the hiatus. A region-adapted algorithm informed by quantitative suspension metrics (Table 1 <ImgLink imgNo="1" imgType="table" />) and integrated concepts (Figure 1 <ImgLink imgNo="1" imgType="figure" />) may improve anatomic restoration, reduce iatrogenic motion restriction, and better address extrusion-prone segments.</Pgraph></TextBlock>
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