25dkg26 10.3205/25dkg26 urn:nbn:de:0183-25dkg267 Meeting Abstract Stoter Stoter Lisa L

Radboudumc, Nijmegen, Netherlands

author Peters Peters Kirsten K

Rijnstate, Arnhem, Netherlands

author Enklaar Enklaar Rosa R

Radboudumc, Nijmegen, Netherlands

author Schulten Schulten Sascha S

Radboudumc, Nijmegen, Netherlands

author Weemhoff Weemhoff Mirjam M

Zuyderland, Heerlen, Netherlands

author van Leijssen van Leijssen Sanne S

Maxima MC, Veldhoven, Netherlands

author van Eijndhoven van Eijndhoven Hugo H

Isala, Zwolle, Netherlands

author Kluivers Kluivers Kirsten K

Radboudumc, Nijmegen, Netherlands

author German Medical Science GMS Publishing House

Düsseldorf

610 20251111 engl This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). M0612 26 Deutsche Kontinenz Gesellschaft e.V. 36. Kongress der Deutschen Kontinenz Gesellschaft Sitzung 12: Joint Session: spezielle Probleme in der Uro-Gynäkologie Bielefeld 20251114 20251115 26 TextIntroduction: While sexual function generally improves after pelvic organ prolapse (POP) surgery, concerns remain de novo dyspareunia . This study compares the effect of the modified Manchester procedure (MP) and the sacrospinous hysteropexy (SSH) on sexual function and dyspareunia.Methods: Analysis of the data on sexual function from a multicentre randomized controlled trial evaluating MP versus SSH in treatment of primary uterine prolapse. The primary outcome was the change in the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire, IUGA-Revised (PISQ-IR) score from baseline to 24 months. Secondary outcomes included dyspareunia incidence and de novo dyspareunia.Results: A total of 393 (MP = 197, SSH=196) women completed the PISQ-IR questionnaire at baseline and after 24 months follow-up. In sexually active patients (MP=101, SSH=99), the mean PISQ-IR score improved within both groups: 0.27 (p= <.001; Cohen’s d= 0.59) points after MP and 0.20 (p= <.001; Cohen’s d= 0.40) points after SSH. There was no difference in PISQ-IR score between the groups at 24 months follow-up (MP 3.46, SSH 3.36; p=.062), nor in the change over time. The occurrence of de novo dyspareunia did not differ significantly (MP 5%, SSH 13%; p= .075).Conclusion: Both MP and SSH lead to a similar improvement in sexual function in sexually active patients, without a difference between procedures. There is no difference in de novo dyspareunia rates after MP compared to SSH. In view of higher effectivity, the MP should be considered as a surgical option for POP, without concern for a negative impact on sexual function. Fatton B de Tayrac R Letouzey V Huberlant S Pelvic organ prolapse and sexual function 2020 Nat Rev Urol 373-90 Fatton B, de Tayrac R, Letouzey V, Huberlant S. Pelvic organ prolapse and sexual function. Nat Rev Urol. 2020;17(7):373-90. 0 0 0 0