25dkou614 10.3205/25dkou614 urn:nbn:de:0183-25dkou6146 Meeting Abstract Jukema Jukema Gerrolt G

University Hospital Zurich, Zurich, Schweiz

author Lempert Lempert Maximilian M

University Hospital Zurich, Zurich, Schweiz

author Salfelder Salfelder Clara C

University Hospital Zurich, Zurich, Schweiz

author German Medical Science GMS Publishing House

Düsseldorf

610 20251031 engl This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. Dieser Artikel ist ein Open-Access-Artikel und steht unter den Lizenzbedingungen der Creative Commons Attribution 4.0 License (Namensnennung). M0634 614 Deutsche Gesellschaft für Orthopädie und Unfallchirurgie Deutsche Gesellschaft für Orthopädie und Orthopädische Chirurgie Deutsche Gesellschaft für Unfallchirurgie Berufsverband für Orthopädie und Unfallchirurgie Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2025) Abstracts | Freie Themen 1 Berlin 20251028 20251031 AB98-4396 TextObjectives and questions: Full thickness traumatic soft tissue defects are difficult to treat. Mesh graft transplantation alone causes frequently instable scar ulcerations with need for revision surgery. For that reason, in our study we used a collagen-elastin scaffold combined with mesh graft to improve wound healing and to reduce scar ulcerations and revision surgery.Material and methods: In the period 3.2013 – 3.2020 45 trauma wounds from different types of injuries were treated with a collagen-elastin scaffold (Matriderm®, MD) augmented mesh graft. The wounds were separated in three subgroups (soft tissue injury (ST), closed fracture with soft tissue injury (F), open fracture (OF). Outcome variables were recurrence of wound defects with revision surgery and reduction of bacterial strains. For statistical analysis Student’s t-test, ANOVA, Mann-Whitney U test, and Pearson’s chi-squared test was used.Results: For the rate of recurrence there was no significant difference between the three groups (F: 0%; OF: 11.1%; ST: 9.5%). The duration of VAC/NPWT therapy for preconditioning the wounds, significantly differed between the groups (F: 10.8 days; OF 22.7 days; ST: 12.6 days (p<0.05)). With NPWT a clinically significant reduction of bacterial burden was achieved (bacterial shift (mean (SD), F: -2.25 (1.89); OF: -1.9 (1.37); ST:-2.6 (2.2)). Discussion and conclusions: For the rate of recurrence there was no significant difference between the three groups (F: 0%; OF: 11.1%; ST: 9.5%). The duration of VAC / NPWT therapy for preconditioning the wounds, significantly differed between the groups (F: 10.8 days; OF 22.7 days; ST: 12.6 days (p<0.05)). With NPWT a clinically significant reduction of bacterial burden was achieved (bacterial shift (mean (SD), F: -2.25 (1.89); OF: -1.9 (1.37); ST:-2.6 (2.2)). 0 0 0 0